p>MSc Project title New technique of radiolabelling tracer with 64Cu for positron emission particle tracking (PEPT)
(Duration: Feb 2013 to Dec 2014)
Positron Emission Particle Tracking (PEPT) is a non-invasive technique used for obtaining direct information about the flow within industrial systems. It involves tracking the motion of a tracer particle labelled with a PET radionuclide using a Positron Emission Tomography (PET) camera. PEPT Cape Town, housed at iThemba LABS, hosts two PET cameras modified for PEPT and produced tracer particles for PEPT experiments on a daily basis. The tracers are typically made using 68Ga (half-life = 68 minutes) or 18F (half-life = 109 minutes), which realistically limits the tracking time to 2 – 3 hours. My work is the development of a new tracer labelling technique using 64Cu (half-life = 12.7 hours) which would allow for much longer tracking times during PEPT experiments. The study consists of three steps: development of a tracer labelling technique for 64Cu tracer particle; comparison of detection efficiency of the 64Cu tracer with 68Ga, 18F, 22Na tracers in the PET scanner; application with positron imaging to assess the usefulness of the 64Cu tracer.
K. E. Cole, A. Buffler, N. P. van der Meulen, J. J. Cillers, J-P. Franzidis, I. Govender, C. Liu, M. R. van Heerden. Positron emission particle tracking measurements with 50 micron tracers. Chemical Engineering Science 75 (2012) 235-242.
K. E. Cole, A. Buffler, J. J. Cilliers, I. Govender, J. Y. Y. Heng, C. Liu, D. J. Parker, U. V. Shah, M. van Heerden, X. Fan. A surface coating method to modify tracers for positron emission particle tracking (PEPT) measurements of froth flotation. Powder Technology. DOI: 10.1016/j.powtec.2014.04.083.
Liu C., Buffler A., Franzidis J-P., van Heerden M., Dolley S. 2013 New technique of radiolabelling tracers with 64CU for positron emission particle tracking. Poster presented at 31st Annual SAIMM Mineral Processing Conference, 6-7 August, Cape Town, South Africa.